某院158例药品不良反应监测报告分析

Monitoring and analysis of 158 ADR in hospital

目的分析药品不良反应（ADR）发生的特点和规律,促进临床用药的安全性和合理性。方法对2014年1月~2015年10月收集的158例药品不良反应报告进行分类统计分析。结果静脉给药方式发生的不良反应例数最多（占74.05%）;导致不良反应的药品以抗感染药最多（占48.73%）;女性发生ADR比例（53.16%）高于男性（46.84%）;不良反应主要以皮肤及其附件损害为主（占43.67%）。结论应加强药品不良反应监测工作,为临床合理用药提供参考依据,减少和防止药品不良反应的发生,确保患者用药安全。

Objective Analyze the characteristics and regularity of adverse drug reactions（ADR） in our hospital to promote the Safety and rationality of clinical medication. Methods A statistical analysis of 158 cases of adverse drug reactions reported in our hospital from January 2014 to October 2015. ResultsThe ADRS were mainly occurred in the way of intravenous administration of drug（74.05%） and in our hospital it mainly caused by anti-infectives（ 48.73%）,The proportion of female ADR was more than that of male, 53.16% and 46.84% respectively, and the clinical manifestations of adverse reactions were skin and its accessories, which accounted for 43.67%.Conclusion We should strengthen the monitoring of ADR not only to provide reference data for rationally clinical application of these drugs, but to reduce and prevent the occurrence of adverse drug reactions for the Safety of Drug Using of Patients.