富血小板纤维蛋白应用于口腔组织再生研究进展

Research advances on platelet-rich fibrin in oral tissue regeneration

富血小板纤维蛋白(platelet-rich fibrin,PRF)是自体来源的富含白细胞、血小板的纤维蛋白生物材料,为第二代血小板浓缩物。PRF中含有多种生长因子,可为参与组织再生的间充质干细胞提供生物性的生长环境;此外,其纤维成分也可起到生物支架作用。文章对PRF应用于口腔组织再生的研究进展做一综述。

Platelet-rich fibrin（PRF）,the second generation of platelet concentrate,is defined as an autologous leukocyte- and platelet-rich fibrin biomaterial. High quantities of growth factors in PRF provide biological environment for mesenchymal stem cells to participate in tissue regeneration,and the fibrin in PRF is used as a biological scaffold. This article summaries the research progress on platelet-rich fibrin in oral tissue regeneration.