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Idiopathic Basal Ganglia Calcification Presented with Progressive Supranuclear Palsy-like Features 被引量:2

Idiopathic Basal Ganglia Calcification Presented with Progressive Supranuclear Palsy-like Features
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摘要 Fahr's disease, or idiopathic basal ganglia calcification (IBGC), is a rare neurological syndrome characterized by abnormal calcified deposits located mostly in bilateral basal ganglia and dentate nucleus, and also in cerebral cortex, thalamus, hippocampus, cerebellar, and subcortical white matter. Clinically, it presents various symptoms, including parkinsonism (presented in 57% of the patientsL chorea ( 19%), tremors (8%), dystonia (8%), athetosis (5%)~ and orofacial dyskinesia (3%). Fahr's disease, or idiopathic basal ganglia calcification (IBGC), is a rare neurological syndrome characterized by abnormal calcified deposits located mostly in bilateral basal ganglia and dentate nucleus, and also in cerebral cortex, thalamus, hippocampus, cerebellar, and subcortical white matter. Clinically, it presents various symptoms, including parkinsonism (presented in 57% of the patientsL chorea ( 19%), tremors (8%), dystonia (8%), athetosis (5%)~ and orofacial dyskinesia (3%).
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2016年第4期478-479,共2页 中华医学杂志(英文版)
关键词 Freezing of Gait Idiopathic Basal Ganglia Calcification Progressive Supranulcear Palsy Freezing of Gait Idiopathic Basal Ganglia Calcification Progressive Supranulcear Palsy
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  • 1Manyam BV, Waiters AS, Narla KR. Bilateral striopallidodentate calcinosis: Clinical characteristics of patients seen in a registry. Mov Disord 2001 ; 16:258-64. doi: 10.1002/rods. 1049.
  • 2Kim TW, Park IS, Kim SH, Lee KS, Kiln YI, Kim JS. Striopallidodentate calcification and prngressive supranuclear palsy-like phenotype in a patient with idiopathic hypoparathyroidism. J Clin Neurol 2007;3:57-61. doi: 10.3988/jcn.2007.3.1.57.
  • 3Williams DR, Holton JL, Strand K, Revesz T, Lees AJ. Pure akinesia with gait freezing: A third clinical phenotype of progressive supranuclear palsy. Mov Disord 2007;22:2235-41. doi: 10.1002/rods.21698.
  • 4Chen W J, Yao XP, Zhang QJ, Ni W, He J, Li HF, et aL Novel SLC20A2 mutations identified in southern Chinese patients with idiopathic basal ganglia calcification. Gene 21)13;529:159-62. doi: I 0.1016/j.gene.2013.07.071.

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