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非小细胞肺癌靶向药物治疗相关基因检测的规范建议 被引量:23

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摘要 一、检测非小细胞肺癌(NSCLC)常见靶向治疗相关基因的意义 肺癌是世界范围内发病率及病死率均居于首位的恶性肿瘤,其中NSCLC约占85%左右。随着对其分子途径探索的逐步深入和相对应的靶向药物的不断出现,给其中的部分晚期患者带来了新的希望。
出处 《中华病理学杂志》 CAS CSCD 北大核心 2016年第2期73-77,共5页 Chinese Journal of Pathology
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  • 1董强刚,黄进肃,黄建,卢丽琴,杨立民.肺癌靶向治疗研究进展与我国肺癌的EGFR基因突变概况[J].肿瘤,2005,25(6):625-628. 被引量:35
  • 2谭卓毅,丁梅,王保捷.福尔马林固定石蜡包埋组织中DNA提取[J].法医学杂志,2006,22(6):455-458. 被引量:32
  • 3Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or Carboplatin-Paclitaxel in pulmonary adenocarcinoma [J]. N Engl J Med , 2009,361 (10) : 947-957.
  • 4Maemondo M, Inoue A, Kobayashi K, et al. Gefitinib or Chemotherapy for non-small-cell long cancer with mutated EG-FR [J]. N Engl J Med, 2010,362(25) : 2380-2388.
  • 5Mitsudomi T, Morita S, Yatabe Y, et al. Gefitinib versus Cisplatin plus Docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial [J]. Lancet Oncol, 2010, 11(2) : 121-128.
  • 6Zhou C, Wu YL, Chen GY, et al. On behalf of the OPTIMAL investigators. Efficacy results from the randomised phase Ⅲ optimal (ctong 0802) study comparing first-line Erlotinib versus Carboplatin (cbdca) plus Gemcitabine (gem), (nsclc) in Chinese advanced non-small-cell lung cancer patients (pts) with EGFR activating mutations [J]. Ann Oncol, 20!0,21 ( suppl 18) : LAB 13.
  • 7Rosell R, Moran T, Queralt C, et al. Screening for epidermal growth factor receptor mutations in lung cancer [J]. N Engl J Med, 2009,361 (10) : 958-967.
  • 8Dahabreh IJ, Linardou H, Siannis F, et al. Somatic EGFR mutation and gene copy gain as predictive biomarkers for response to tyrosine kinase inhibitors in non-small cell lung cancer [J]. Clin Cancer Res, 2010, 16( 1 ) : 291-303.
  • 9Yang CH, Fukuoka M,Mok TS, et al. Final overall survival results from a phase Ⅲ , randomised, open-label, first-line study of Gefitinib vs Carboplatin / Paclitaxcl in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS) [J]. Ann Oncol, 2010,21 (suppl 8):LAB 2.
  • 10NCCN Clinical Practice Guidelines in Oncology: Non-small Cell Lung Cancer. NCCNorg 2011 ; version.2.

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