针灸治疗肾虚痰湿型多囊卵巢综合征的临床研究

Clinical Study on Acupuncture and Moxibustion Therapy for Polycystic Ovary Syndrome( PCOS) with Kidney Deficiency and Phlegm- dampness Type

目的:观察针灸治疗肾虚痰湿型多囊卵巢综合征的临床疗效,并试探讨其作用机制。方法:将63例肾虚痰湿型多囊卵巢综合征患者随机分为针灸组(32例)、电针组(31例)。电针组穴取三阴交、气海、关元、大赫、子宫、肾俞、脾俞、次髎等主穴,针刺得气后连接电针,刺激时间为20 min,每周治疗3次。针灸组采用针刺加温灸盒灸法治疗。两组均治疗3个月经周期,随访3个月。观察两组的临床疗效、睾酮(T)、雌二醇(E2)、黄体生成素(LH)、卵泡刺激素(FSH)及两者比值(LH/FSH)的变化。结果:针灸组总有效率为81.25%,电针组总有效率为61.29%,针灸组疗效与电针组相比有明显统计学意义;针灸组治疗后患者血清相关性激素T值显著降低(P<0.01),而E2值则显著升高(P<0.01),均较电针组差异有统计学意义(均P<0.05)。针灸组治疗后患者血清相关性激素LH值、LH/FSH值显著降低(P<0.01),而FSH值则升高,但均较电针组差异无统计学意义(均P>0.05)。结论:针刺加温灸盒灸法治疗肾虚痰湿型多囊卵巢综合征总体临床疗效优于单纯针刺治疗,并可有效降低T值、升高E2值。提示该法是治疗肾虚痰湿型多囊卵巢综合征的一种较好治疗方法,值得临床推广应用。

Objective： To observe the therapeutic effect of acupuncture and moxibustion on polycystic ovary syndrome（ PCOS） with kidney deficiency and phlegm- dampness type,and to explore its mechanism. Methods：63 patients in accordance with the diagnosis were randomly divided into 32 cases in acupuncture and moxibustion（ AM） group and 31 cases in pure electro- acupuncture（ EA） group. In MA group,we used electro- acupuncture at Sanyinjiao（ SP6）,Qihai（ RN6）,Guanyuan（ RN4）,Dahe（ KL12）,Zigong（ EX CA1）,Shenshu（ BL23）,Pishu（ BL20）,Ciliao（ BL32） and other main points. After arrival of Qi,electric stimulation was attached to the acupoints for 20 minutes. The treatment was given three times a week,combining with moxibustion,for a 3- month observation. In EA group,the selection of points and acupuncture treatment course were the same with those in AM group. The clinical efficacy was assessed in both groups. Meanwhile,we detected the changes of estradiol（ E2）,testosterone（ T）,luteotropic hormone（ LH）,follicle stimulating hormone（ FSH） and LH / FSH between two groups. Results： The total effective rate was 81. 25% in the AM group,and it was61. 29% in the EA group. There was a significant difference between two groups. Treatment led to the decrease of T level and the increase of E2 level in both AM and EA groups. Moreover,AM group had a lower T level（ P 〈0. 01）,and a higher E2 level in serum（ P 〈0. 01）,compared with those in EA group. After treatment,levels of LH and LH / FSH were both reduced significantly in two groups（ P 〈0. 01）,while the levels of FSH were increased. However,there was no significance in LH,FSH and LH / FSH between two groups（ all P 〈0. 05）. Conclusion： It has a better effect on the improvement of T and E for acupuncture and moxibustion for treating PCOS with kidney deficiency and phlegm- dampness type,which suggests that as a good method for treating PCOS with kidney deficiency and phlegm- dampness type,acupuncture and moxibustion therapy is worthy of clinical application.