高血压、糖尿病、高脂血症对老年脑梗死患者颈动脉粥样硬化的作用

Influence of hypertension,diabetes and hyperlipemia on carotid atherosclerosis in elderly patients with cerebral infarction

目的探讨在老年脑梗死患者中,高血压、糖尿病、高脂血症对颈动脉粥样硬化(carotid atherosclerosis,CAS)发生的影响。方法收集我院≥65岁急性脑梗死患者145例,根据颈动脉彩超结果分组,其中CAS组80例,对照组65例;收集患者高血压、糖尿病、高脂血症患病信息。结果 CAS组高血压(P=0.002)、糖尿病(P=0.021)及高脂血症(P=0.038)的患病率显著高于对照组。经多重Logistic回归分析,高血压(P=0.007)、高脂血症(P=0.032)是老年脑梗死患者CAS的危险因素。结论高血压、高脂血症是影响老年脑梗死患者CAS发生的因素。存在CAS的老年脑梗死患者须更为严格地控制血压、血脂。

Objective To explore the effects of hypertension,diabetes and hyperlipemia on carotid atherosclerosis（ CAS） in the elderly patients with cerebral infarction. Methods The clinical data of 145 patients with acute cerebral infarction（ ≥65 years old） in our hospital were collected. According to the results of carotid ultrasonography,the patients were divided into two groups,CAS group and control group. The clinical data were compared between the two groups.Results The prevalence rate of hypertention（ P = 0. 002）,diabetes（ P = 0. 021） and hyperlipemia（ P = 0. 038） in CAS group were significantly higher than those in control group. Multiple Logistic regression analysis showed hypertension（ P =0. 007） and hyperlipemia（ P = 0. 032） were risk factors of CAS in the elderly patients with cerebral infarction.Conclusions In the elderly patients with cerebral infarction,hypertension and hyperlipemia can influence the occurrence of CAS. It is important to control blood pressure and serum lipid strictly in the elderly patients with cerebral infarction.