新活素治疗急性心肌梗死合并心力衰竭

Efficacy of rh-BNP on acute myocardial infarction complicated with heart failure

目的：探讨新活素治疗急性心肌梗死合并心力衰竭的效果。方法选取2013年9月至2014年9月急性心肌梗死合并心力衰竭患者84例，随机分为两组，每组42例。对照组给予常规治疗，观察组给予常规治疗和新活素，比较两组临床效果。结果观察组显效24例，有效15例，无效3例，总有效率为92.9％；对照组显效18例，有效14例，无效10例，总有效率为76.2％，两组总有效率比较差异有统计学意义（ P＜0.05）；观察组心率、LVEF及NT-ProBNP等均明显低于对照组，差异有统计学意义（ P＜0.05）。结论新活素在治疗急性心肌梗死合并心力衰竭方面临床效果明显，可有效改善患者心功能指标。

Objective To investigate the efficacy of rh-BNP on acute myocardial infarction con-current heart failure .Methods From September 2013 to September 2014,84 patients with acute myocar-dial infarction concurrent heart failure were selected , and they were randomly divided into two group ,with 42 cases in each group .The control group was given conventional therapy , and the observation group was given combined rh-BNP, and compared the two groups of clinical effects .Results In observation group , 24 cases were markedly effective , effective in 15 cases , invalid in 3 cases , the total effective rate was 92.9%, those in control group was 18 cases, 14 cases, 10 cases, and 76.2%.The differences were signif-icant （P〈0.05）;heart rate of patients in the observation group , LVEF and NT-ProBNP was significantly lower than those in the control group , the differences were significant （ P〈0.05） .Conclusions rh-BNP in the treatment of acute myocardial infarction heart failure clinical effect is obvious , while effective on improving the cardiac function in patients .