恶性肿瘤患者合并肺栓塞的临床特点

Clinical characteristics of pulmonary embolism with cancer

目的：探讨恶性肿瘤患者和抗癌治疗相关的肺栓塞的临床特点。方法回顾性分析2009年1月至2014年6月河南省直第三人民医院收治的伴发恶性肿瘤的肺栓塞患者的临床资料。结果本研究中84例肺栓塞患者中47例伴恶性肿瘤，平均年龄64岁。从确诊恶性肿瘤至出现肺栓塞的平均时间为5.5个月。最常见的恶性肿瘤是肺癌（23％），其次是胰胆管癌、胃癌、妇科肿瘤、乳腺癌和肝癌。最常用的化疗药为铂类。结论70％的患者在诊断为恶性肿瘤后1年内确诊出现了肺栓塞。肺癌为最常见的伴发肺栓塞的恶性肿瘤。

Objective To investigate the clinical characteristics of patients with cancer and pulmonary embolism （ PE） related to anticancer treatment .Methods We retrospectively analyzed the clinical data of patients with cancer who were diagnosed with PE from January 2009 to June 2014.Results Fourty-seven patients with cancer of the 84 patients with PE were analyzed .The median age was 64 years.The median time between the cancer diagnosis and the PE diagnosis was 5.5 months.Lung cancer was the most common cancer （23.0%） , followed by pancreatobiliary cancer , stomach canc-er, gynecological cancer , breast cancer , and hepatocellular carcinoma .Platinum-containing chemotherapeutic were com-mon.Conclusions PE was diagnosed within 1 year after the cancer diagnosis in 70% of patients .Lung cancer was the most common cancer .