对我国变应性鼻炎动物实验研究的评价与思考

Evaluation and consideration on animal model of allergic rhinitis in China

目的通过对我国变应性鼻炎动物模型研究现状进行分析,以期对今后变应性鼻炎动物实验研究提出一些设想和建议。方法回顾分析1998年1月-2014年12月国内有关变应性鼻炎模型所用实验动物种类、品系、复制动物模型方法及其判断标准。结果 137篇文章中所用实验动物种类、品系、复制动物模型的方法及其判断标准各异。结论只有标准化、统一化的实验前提,才能保证科研工作的顺利实施和实验结果的可靠性。

OBJECTIVE The purpose of the study is to put forward some ideas and suggestions for the future research of allergic rhinitis.METHODS The experimental animal species,strains,methods of replicating animal model and the judging standard of allergic rhinitis in China from January 1998 to December 2014 were reviewed and analyzed.RESULTS The experimental animal species,strains,methods of replicating animal model and the judging standard of allergic rhinitis used in 137 articles were different.CONCLUSION Only standardized and unified experimental animal model can ensure the implementation of scientific research successfully and the reliability of the experimental results.