阻塞性睡眠呼吸障碍与全身多系统疾病关系的研究进展

Research status of improving the success rate of implant in patients with osteoporosis

阻塞性睡眠呼吸暂停低通气综合征(Obstructive sleep apnea hypopnea syndrome,OSAHS)是一种慢性睡眠呼吸疾病,流行病学资料显示,OSAHS患者中高血压、2型糖尿病、心血管疾病、脂代谢紊乱和卒中的患病率均高于无OSAHS者,其可引起一系列全身性疾病及临床症状(日间嗜睡、头晕、记忆力减退及性格改变等)。本文就OSAHS疾病与脂代谢、糖尿病、心脑血管疾病之间的相关关系作一综述,总结OSAHS导致系统性疾病的发病机制,探讨OSAHS疾病与多种全身性疾病之间可能存在的因果关系。

Obstructive： sleep apnea hypopnea syndrom （Obstructive sleep apnea hypopnea syndrome, OSAHS） is a chronic sleep respiratory disease, the epidemiological data show that the prevalence of hypertension, type 2 diabetes, cardiovascular disease, lipid metabolic disorder and stroke in patients with OSAHS were higher than those without OSAHS. OSHAS can cause a series of systemic diseases and clinical symptoms （daytime drowsiness, dizziness, memory loss and personality change, etc.） This article presents a comprehensive review of the relationship between the OSAHS and lipid metabolic disease, diabetes, cardiovascular disease,concludes the pathogenesis of OSAHS resulting in systemic disease,explores the possible causal relationship between a variety of systemic diseases and OSAHS.