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中性粒细胞性哮喘临床特征分析

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摘要 目的:分析中性粒细胞性哮喘患者的临床特点。方法:收集2013年1月~2014年12月,我院门诊及住院接受治疗的中性粒细胞性哮喘患者42例,回顾分析其临床资料,总结其临床特点。结果:42例患者的诱导痰中性粒细胞比均≥61%,女性占69.05%,显著高于男性30.95%(P<0.05);发病年龄集中于12岁以后(78.57%);10例(23.81%)重症,24例(57.14%)急性加重;FEV1%pred>80%仅占14.29%,57.14%<60%;可逆程度平均为11.74±1.22%;患者的中性粒细胞比为75.76±9.82%,显著高于嗜酸性粒细胞比2.43±2.36%(P<0.05)。结论:中性粒细胞性哮喘患者多病情严重,临床表现成多样性,早期诊断难度较大,充分探讨中性粒细胞炎症在哮喘中的发生机制,对于临床诊断及治疗具有重要意义。
作者 杨明宇
出处 《中国伤残医学》 2016年第4期13-14,共2页 Chinese Journal of Trauma and Disability Medicine
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