金水宝胶囊联合替米沙坦治疗原发性肾病综合征患者的临床疗效

Jinshui Bao Capsule Combined with Telmisartan in the Treatment of Primary Nephrotic Syndrome Patients

目的探讨金水宝胶囊联合替米沙坦治疗原发性肾病综合征患者的临床疗效。方法选取2012年8月至2013年11月辽阳市中心医院收治的88例原发性肾病综合征患者作为研究对象,按随机数字表法将其分为对照组和观察组,各44例。对照组患者单纯采用泼尼松进行治疗,观察组患者在对照组基础上加用金水宝胶囊和替米沙坦,比较两组患者的临床疗效、24 h尿蛋白定量、血肌酐、血浆清蛋白水平。结果治疗后,观察组患者的24 h尿蛋白定量、血肌酐均明显低于对照组,血浆清蛋白明显高于对照组,差异均有统计学意义(均P<0.05);观察组患者的完全缓解率及总有效率均明显高于对照组,差异均有统计学意义(均P<0.05)。结论金水宝胶囊联合替米沙坦治疗原发性肾病综合征患者临床疗效明显,可有效改善患者的临床症状。

Objective To investigate Jinshui capsule combined with telmisartan in the treatment of primary nephrotic syndrome patients.Methods From November 2013 to August 2012,88 cases of primary nephrotic syndrome in Liaoyang city hospital were selected as the research object,according to the random number table method,the control group and observation group,44 cases.Patients in the control group treated with prednisone treatment,to observe clinical curative effect of the patients in the control group based on the use of Jinshuibao capsule and telmisartan, compared two groups of patients,24 h urine protein,serum creatinine,serum albumin level.Results After the treatment were observed group of patients with 24 h urinary protein,serum creatinine were significantly lower than that of the control group,plasma albumin was significantly higher than the control group,differences were statistically significant（P〈0.05）;observation group of patients with complete remission rate and total effective rate were signify- cantly higher than those in the control group,differences were statistically significant（P〈0.05）.Conclusion Jinshui treasure capsule combined with telmisartan in treatment of primary nephrotic syndrome patients clinical curative effect,can effectively improve the patient＇s clinical symptoms.