中医药二联疗法治疗成人大骨节病临床疗效观察

Observation on clinical curative effect of Traditional Chinese Medicine combination therapy on adult Kashin-Beck disease

目的观察中医药二联疗法对成人大骨节病的临床疗效,选出质优、价廉、疗效好和副作用小的治疗方法。方法选择确诊的成人大骨节病患者69例,随机分成中医药二联疗法治疗组34例和西医组35例,中医药二联疗法治疗组给予自拟内服汤药制剂和离子导入治疗,西医组给予口服硫酸软骨素和维生素E。结果治疗前后西医组(t=9.418)和中医组(t=7.662)的临床疗效差异有统计学意义(均P<0.05);总有效率中医组79.41%、西医组51.43%,中医组高于西医组,差异有统计学意义(χ2=5.953,P<0.05);治疗后中医组和西医组比较,中医组关节休息痛得分(t=1.787)和四肢活动能力得分(t=2.793)高于西医组,差异有统计学意义(均P<0.05)。结论中医药二联疗法可以提高成人大骨节病的显效率和总有效率,对改善患者四肢运动能力和关节休息痛的治疗效果明显,具有推广价值。

Objective To observe clinical curative effect of Traditional Chinese Medicine（TCM） combined therapy on adult Kashin-Beck disease（KBD）, in order to select a treatment of cheap, good curative effect and little side effect for the prevention and treatment of KBD. Methods Sixty-nine cases confirmed with adult KBD were randomly divided into group treated by TCM combined therapy（34 cases） and Western medicine group（35 cases）. TCM combined therapy group were administrated with self oral decoction preparation and iontophoresis, while the Western medicine group received oral chondroitin sulfate and vitamin E. Results The clinical curative effect was of statistical differences（P0.05） in Western medicine group（t=9.418）and TCM combined therapy treatment group（t=7.662） before and after the treatment. The total effective rate was 79.41% in the TCM combined therapy treatment group, and 51.43% in the Western medicine group, with statistical difference between the two groups（χ2=5.953,P0.05）. After the treatment, the scores of joint pain at rest（t=1.787） and limbs locomotor activity（t=2.793） were better in the TCM combined therapy group than in the Western medicine group, with statistical difference（P0.05）. Conclusions TCM combined therapy can significantly improve the efficiency of adult KBD and total efficiency, and is of obvious treatment effectiveness of improving exercise capacity of patients with limb and joint pain. It is a method for treatment with promotional value.