正常高值血压者的中心动脉压对动脉弹性功能的影响

The changes of central blood pressure and artery elasticity in individuals with high-normal blood pressure

目的探讨正常高值血压者中心动脉压与动脉弹性的变化。方法选取在医院体检中心行健康体检者138例,根据血压分为理想血压组72例和正常高值血压组66例,采用Ormon-Colin公司的无创桡动脉脉波检测装置测量中心动脉收缩压(CSBP),应用Complior脉搏波速度测定仪测量颈股脉搏波传导速度(cfPWV)。采用回归分析方法比较CSBP与cfPWV的变化及两者的相关性。结果正常高值血压组中心动脉压和cfPWV均高于理想血压组(均P<0.05)。中心动脉压与cfPWV呈正相关(r=0.53,P<0.01)。逐步回归分析显示中心动脉压是cfPWV的主要影响因素(β=0.449,P<0.01)。结论正常高值血压者中心动脉压增高,动脉弹性下降。

Objective To evaluate the changes of central blood pressure and artery elasticity in individuals with high- normal blood pressure （HNBP）. Methods A total of 138 subjects underwent health examination were divided into ideal blood pressure group （n=72） and HNBP group （n=66） according to blood pressure. The central systolic blood pressures （CSBP） was measured indirectly by Ormon- Colin non- invasive radial artery pulse wave measurement device, and carotid- femoral pulse wave velocity （cfPWV） were measured by Complior device. Regression analysis was performed to determine the relationship between CSBP and cfPWV. Results CSBP and cfPWV were significantly higher in HNBP group than in ideal blood pressure group （P〈0.01）. CSBP was positively related to cfPWV （r=0.53, P〈0.01）. Stepwise regression analysis showed that CSBP was the risk factor for cfPWV （β=0.449, P〈0.01）. Conclusion Central blood pressure increases with decrease of artery elasticity in individuals with normal- high blood pressure.