奥美拉唑治疗胃溃疡合并出血58例疗效分析

Analysis of Omeprazole in the Treatment of Gastric Ulcer Complicated With Hemorrhage in 58 Cases

目的探讨奥美拉唑治疗胃溃疡合并出血的临床效果。方法将100例胃溃疡合并出血患者分为观察组(58例)和对照组(42例),分别加用奥美拉唑治疗和给予常规对症治疗,比较两组临床治疗效果。结果观察组平均止血时间和溃疡愈合时间均短于对照组,治疗总有效率(93.1%)和HP转阴率均(83.7%)高于对照组(85.7%、58.8%),胃出血复发率(5.2%)低于对照组(23.8%),比较差异有统计学意义(P<0.05)。结论奥美拉唑治疗胃溃疡合并出血疗效确切,复发率低。

Objective To explore the clinical effect of omeprazole in the treatment of peptic ulcer hemorrhage. Methods 100 cases of gastric ulcer with hemorrhage were divided into observation group（58 cases） and control group（n = 42）, plus omeprazole treatment and given routine symptomatic treatment, respectively, compared two groups of clinical curative effect. Results Observation group, the average time to hemostasis and ulcer healing time were shorter than that of the control group treatment, the total efficiency（93.1%） and HP negative rate were（83.7%） higher than that of the control group（85.7%, 58.8%）, gastric bleeding recurrence rate（5.2%） lower than that of the control group（23.8%）, the difference was statistically significant（P〈0.05）. Conclusion The effect of omeprazole in the treatment of gastric ulcer with hemorrhage is exact, the recurrence rate is low.