小儿慢性胃炎内镜表现与胃黏膜病理组织学改变的相关性分析

Correlation Analysis between Endoscopic Findings and Pathological Changes of Gastric Mucosa in Children with Chronic Gastritis

目的:分析小儿慢性胃炎患儿内镜检查与病理组织学改变的相关性。方法:研究对象为本院自2010年3月至2013年3月收治的186例慢性胃炎儿童,均接受胃镜和病理学两种方式诊断,评价并分析镜下表现与病理学相关性。结果:经胃镜诊断结果为178例慢性浅表性胃炎(CSG),8例慢性萎缩性胃炎(CAG)。病理学诊断结果为170例CSG,10例CAG,6例胃黏膜无损害。胃镜与病理学诊断CSG的准确度为90.32%,胃镜与病理学诊断CAG的准确度为93.54%。对CSG的阳性预测值中,红白间隔、红色居多及充血水肿占92.42%和92.96%。病理组织学性的溃烂、活动性炎症、肠上皮化生与胃镜下各种表现的关系均不够密切。胃镜与病理学诊断CSG和CAG的灵敏度分别为97.06%和30.00%,差异具有显著性(P<0.05)。结论:儿童CSG镜下主要形态对病理诊断CSG的灵敏性好且有相关性,而胃镜诊断CAG对病理诊断CAG的灵敏性差。

Objective： To analyze the correlation between endoscopic findings and pathological changes of gastric mucosa in children with chronic gastritis. Method： A total of 186 children with chronic gastritis, who were admitted to Children Affiliated Hospital of Suzhou University from March 2010 to March 2013, were chosen as subjects and diagnosed with endoscopy and pathology. The correlation between endoscopic findings and pathology was evaluated and analyzed. Result： The endoscopic diagnosis results showed that 178 children had chronic superficial gastritis（CSG） and 8 children had chronic atrophic gastritis（CAG）. The pathological diagnosis results showed that 170 children had CSG, 10 children had CAG and 6 children didn＇t have gastr children had CAG and CSG were97.06% and 30% respectively, the differences were significant（P〈0.05）. Conclusion： The main findings of endoscopy for CSG has high sensitivity and is correlated to the diagnosis of pathology for CSG in children, while the diagnosis of endoscopic for CAG has low sensitivity to the diagnosis of pathology for CAG.