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三叉神经痛发病机制的研究进展 被引量：5

Advances in the pathogenesis of trigeminal neuralgia
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摘要 三叉神经痛（TN）的临床治疗困难,严重影响患者日常生活质量,长期反复发作可导致抑郁.目前对于三叉神经痛的发生机制尚不明确,此文就TN的发病机制研究进展作一综述,意在为TN的临床治疗提供新的理论根据. The treatment of trigeminal neuralgia （TN） is still difficult and serious.TN affects the quality of life.The mechanism of trigeminal neuralgia is not very clear until now.This article reviews the researching progresses on the pathogenesis of TN in order to provide a new theoretical basis for the treatment of TN.
作者 张悦 赵姣妹 欧册华
机构地区 四川医科大学附属第一医院(泸州医学院附属医院)疼痛科
出处 《实用疼痛学杂志》 2015年第5期383-386,共4页 Pain Clinic Journal
关键词 三叉神经痛 发病机理 进展 Trigeminal neuralgia Pathogenesis Advances
分类号 R745.11 [医药卫生—神经病学与精神病学]
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参考文献26

  • 1Votrubec M, Thong I. Neuropathic pain-a management update [J]. Aust Faro Physician,2013,42(3): 92-97.
  • 2KooPman JS, Dieleman JP, Huygen FJ, et al. Incidence of facial pain in the general population [ J ]. Pain, 2009, 147 ( 1- 3) :122- 127.
  • 3Dieleman JP, Kerklaan J, Huygen FJ, et al. Incidence rates andtreatment of neuropathic pain conditions in the general popula- tion[J]. Pain,2008,137(3): 681-688.
  • 4Hall GC, Carroll D, Parry D, et al. Epidemiology and treatment of neuropathic pain: the U K primary care perspective [ J ]. Pain, 2006, 122(1-2):156-162.
  • 5Zakrzewska JM. Medical management of trigeminal neuropathic pains[J]. Expert Opin Pharmaeother,2010, 11(8): 1239-1254.
  • 6Yang M, Zhou M, He L, et al. Non-antiepileptic drugs for trigemi- nal neuralgia [J]. Cochrane Database Syst Rev, 2011, 19 (1): CD004029.
  • 7Richard JW. Herpes simplex viruscs//Bernard NF, Peter M, Diane E, eds. Fields Virology. 4th. Philadelphia: Lippincott Williams and Wilkins, 2001 : 2461-2509.
  • 8Khanna KM, Bonncau RH, Kinchington PR, et al. Herpes simplex virus-specific memory CD8 T cells are selectively activated and retained in latently infected sensory ganglia [ J]. Immunity, 2003, 18(5):593-603.
  • 9Dosa S, Castellanos K, Bacsa S, et al. Chronic progressive deficits in neuron size, density and number in the trigeminal ganglia of mice latently infected with herpes simplex virus [J]. lrain Pathol, 2011,21(5): 583-593.
  • 10Dandy WE. Concerning the cause of trigeminal neuralgia [J]. Am J Surg. 1934,24(2): 447-455.

二级参考文献11

  • 1Sessle B J. Neural mechanisms and pathways in craniofacial pain[J].Canadian Journal of Neurological Sciences,1999,(Suppl3):S7-S11.
  • 2McGivern J G. Targeting N-type and T-type calcium channels for the treatment of pain[J].Drug Discovery Today,2006,(5-6):245-253.
  • 3Aegusa H,Matsuda Y,Tanabe T. Effects of ablation of N-and R-type Ca2+ channels on pain transmission[J].Neuroscience Research,2001,(01):1-7.
  • 4Bradbury E S,Burnstock G,McMahon S B. The expression of P2X3 purinoceptors in sensory neurons effects of axotomy and glial-derived neurotrophic factor[J].Molecular and Cellular Neuroscience,1998,(4-5):256-268.
  • 5Nguyen D,Deng P,Matthews E A. Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and behavioral hypersensitivity[J].MOLECULAR PAIN,2009.6.
  • 6Davies A,Kadurin I,Alvarez-Laviada A. The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins,a posttranslational modification essential for function[J].Proceedings of the National Academy of Sciences(USA),2010,(04):1654-1659.
  • 7Tao J,Liu P,Xiao Z. Effects of familial hemiplegic migraine type 1 mutation T666M on voltage-gated calcium channel activities in trigeminal ganglion neurons[J].Journal of Neurophysiology,2012,(06):1666-1680.
  • 8Park J,Luo Z D. Calcium channel functions in pain processing[J].Channels (Austin),2010,(06):510-517.
  • 9解敏,刘悦雁,雷洁,王元银,王烈成.PKA参与ATP对大鼠背根神经节神经元电压门控性钙通道的抑制[J].安徽医科大学学报,2010,45(3):285-289. 被引量：3
  • 10雷洁,王元银,刘安东,解敏,杨晨,陈叶俊,赵莉莉,孙辉,周健,王烈成,张志愿.ATP对大鼠三叉神经节小直径神经元胞内钙浓度的调制作用及其机制[J].中国药理学通报,2010,26(11):1450-1454. 被引量：8

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实用疼痛学杂志
2015年 第5期

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