红景天泡腾片的制备

Preparation of Rhodiola rosea effervescent tablet

研究红景天泡腾片的制备工艺,确定原辅料的配比。选取具有抗疲劳、抗缺氧效果的红景天、Vc等做为主料,其他成分为辅料,以崩解时限、感官质量为评价指标,制作红景天泡腾片。工艺采用酸碱分开湿法制粒,并通过正交试验优化产品配方。结果表明,最佳配方为:红景天提取物26%,酒石酸14.1%,碳酸氢钠43.9%,聚乙烯吡咯烷酮(PVP)2.5%,Vc10%,甜菊糖苷0.5%,聚乙二醇(PEG)6000为3%。

To study the preparation procedure and optimal formula of Rhodiola rosea effervescent tablet.The antifatigue,anti hypoxia effect of Rhodiola rosea and Vc were selected as main material,other ingredients as accessories,the disintegration time and sensory quality as the evaluation index,the Rhodiola rosea effervescent tablet was studied.The formula was optimized by orthogonal tests by acidbase separated aqueous granulation.Results：The optimal formula was as follows：26%Rhodiola rosea extract,14.1%tartaric acid,43.9%NaHCO_3,2.5%polyvinylpyrrolidone（PVP）,10%vitamin C,0.5%stevia sugar,3%polyethylene glycol（PEG） 6000.