强功率雾化机在肺全气道雾化中的应用

Application of High-Power Atomizer in Producing Total Aerosol Contrast Agent in Lungs and Full Airways

目的探讨强功率雾化机雾化造影剂的功效,寻求呼吸性疾病的早期诊断方法。方法采用强功率雾化机,将X线造影剂雾化为气雾造影剂,分别对人及猪肺标本进行雾化造影成像,具体方法如下:受试者主动将气雾造影剂吸入气道内,经反复缓慢深吸气后进行胸部造影成像;将气雾造影剂持续喷入猪肺标本气道口后进行造影成像。结果人肺图像可较为清晰地显示出部分近端气道,且人体无任何刺激感;猪肺标本图像可清晰显示出气管、支气管、细支气管以及肺泡。结论猪肺标本各段支气管图像均达到诊断要求;人肺部分气道图像较为清晰,但未达到诊断要求,可通过提高雾化量的方法,使图像更为清晰,以达到诊断要求。

Objective To investigate the function and effectiveness of the high-power atomizer in producing aerosol contrast agent so as to find the method for the diagnosis of respiratory diseases in early stages. Methods The high-power atomizer was adopted to atomize the X-ray contrast agent into aerosol contrast agent. Then aerosol contrast imaging was produced in human lungs and pig lungs. The specific methods are listed as the following steps： the subject actively inhaled the aerosol contrast agent into airways through oropharynx; a chest film was after the subject breathed in deeply, slowly, and repeatedly; the spraying aerosol contrast agent was continuously and directly shot into the airways of pig lung specimens; then imaging was produced. Results The human chest films clearly show parts of proximal airway images without causing any irritation to the airway, whereas the film of pig lung specimens show clear images from trachea, bronchus and bronchioles, to pulmonary alveoli. Conclusion Each section of the bronchus images of the passively-sprayed pig lung specimens can meet the diagnostic demands and provide accurate location of lesion for clinical treatment. Although part of the pulmonary airway forms images produced after patient inhales aerosol contrast agent, but it cannot meet the diagnostic demands. By increasing the aerosol amount, the imaging can be clearer to meet the diagnostic standards.