几种灭菌包装材料对微生物的阻隔效果研究

Study on the effect of different sterilization packaging materials on the microbial barrier

目的研究灭菌包装材料阻菌效果,建立＂透气包装材料微生物屏障分等试验＂评价标准。方法采用YY/T 0681.10-2011医药行业标准中的透气包装材料微生物屏障分等试验方法,对棉布,无纺布,皱纹纸和纸塑包装袋等4种包装材料阻菌性能进行实验室研究。结果透气包装材料微生物屏障分等试验中,一层至三层的棉布包装后阻菌率的平均值为37.66%~61.11%,皱纹纸包装后阻菌率的平均值为90.42%~94.39%,无纺布包装后阻菌率的平均值为92.19%~98.89%,压力蒸汽用特卫强包装后阻菌率的平均值为80.74%。只有皱纹纸和无纺布微生物阻菌率均〉90%。结论无纺布和皱纹纸阻菌率每次试验均达到90%以上,棉布和纸塑袋阻菌率低于前2种包装材料。

Objective To study the bacteria resistance effect of sterilization packaging material,so as to establish the ＂breathable microbial barrier packaging materials classification experiment＂ evaluation standard. Methods The breathable microbial barrier packaging materials classification experiment in YY / T 0681. 10- 2011,the pharmaceutical industry standard was used to study the four kinds of packaging materials such as the cotton cloth,non- woven,non- woven fabrics and paper- plastic bag for their bacteria resistance performance. Results For the breathable microbial barrier packaging materials classification experiment,one to three layers of cotton cloth after packaging for bacterial blocking rates were37. 66% - 61. 11%,the average bacteria blocking rates after the wrinkle paper packaging were 90. 42% to 94. 39%,the average bacteria blocking rates after non- woven packaging after were 92. 19% - 98. 89%,the average bacteria blocking rate of pressure steam after packing in tyvek was 80. 74%. Only the blocking rate of crepe paper and non- woven was 90%. Conclusion The bacteria blocking rate of non- woven and crepe paper for each test can achieve 90%. The bacteria blocking rates of cotton and paper- plastic bag are lower than those of the first two kinds of packaging materials.