某院神经外科住院患者醒脑静注射液使用情况调查

Investigation of Xingnaojing Injection Applied in the Patients of Neurosurgery Department in a Certain Hospital

目的：调查某院神经外科醒脑静注射液（XNJI）使用情况,为促进XNJI的临床合理应用提供参考。方法：回顾性抽查某院2014年1月～2015年6月神经外科200份使用XNJI的住院病历,对其用药适应证、用法用量、疗程、联合用药、不良反应等进行统计分析。结果：该科室XNJI存在超说明书用药情况,其中超说明书适应证者达34.50%,超剂量给药者达92.50%,而单次用药剂量为40 ml的患者占90.00%。临床使用中也存在着XNJI与西药联合使用的问题,主要与氯化钾（74.00%）合用或与氯化钾和胰岛素（11.00%）联合使用。结论：临床使用醒脑静注射液存在着某些不合理的情况,应加强其规范使用的管理。

Objective： To investigate the application of Xingnaojing injection（ XNJI） in the patients of neurosurgery department to provide reference for the rational drug use. Methods： The retrospective investigation was applied to survey 200 hospitalization records with XNJI from a certain hospital between January 2014 and June 2015. The usage,dosage,medication purpose,course of treatment,compatibility and adverse effects of XNJI were analyzed. Results： The unlabeled use of XNJI was found in neurosurgery department,and 34. 50% of the surveyed patients were found that their diagnoses didn＇t conform to the indications in the medicine specification of XNJI. Moreover,92. 50% of the inpatients were treated with overdose and almost 90. 00% were treated with single drug dose of 40 ml.It was also found that XNJI was often combined with potassium chloride or with potassium chloride plus insulin in clinical use. Conclusion： There is some irrational use of XNJI in clinics,thus the use and management of traditional Chinese medicine injections should be strengthened and regulated.