摘要
背景右旋氯胺酮在欧美各国已广泛使用，与我国临床使用的消旋氯胺酮比较，其麻醉、镇痛效应更强，精神副反应及分泌物更少，苏醒时间更短。目的综述右旋氯胺酮的临床应用，为该药在国内麻醉中的应用提供参考。内容就右旋氯胺酮在麻醉诱导与维持、疼痛治疗、ICU的镇静镇痛及小儿麻醉等方面的临床应用进行归纳总结。趋向使右旋氯胺酮更加安全、有效、广泛地应用于临床。
Background S （＋）-ketamine is now widely used in Europe and America. Compared with racemic ketamine used in clinic in China, S （＋）-ketamine has a better drug action in anesthesia and analgesic, less side effects in psyche, less secretion, and more rapid recovery from anesthesia. Objective The aim of this review was to describe the advances of clinical use of S （＋）- ketamine and provide a practical guidance in clinical anesthesia in our country. Content It has been demonstrated that S （＋）- ketamine plays a large role in such aspects as induction and maintenance of anesthesia, pain treatment, sedation analgesia in ICU, and pediatric anesthesia. Trend S （＋）-ketamine will be more safely, effectively and widely utilized in clinic in future.
出处
《国际麻醉学与复苏杂志》
CAS
2016年第2期149-152,共4页
International Journal of Anesthesiology and Resuscitation
