新疆伊犁地区HBV初筛阳性献血者确证结果分析

Analysis and assessment of reactive blood donors with HBV infection in Yili,Xinjiang

目的做好初筛阳性献血者确证与召回策略研究工作,更好地维护献血者权益。方法收集伊犁地区2013-2014年无偿献血者中HBV阳性献血者的标本,采用2种不同厂家的ELISA试剂及TMA核酸检测技术对22 287份标本进行HBV初筛检测,任一种试剂或方法结果为阳性者做确证试验,根据确证结果进行追踪检测。结果HBV初筛结果阳性75例,确证试验阳性30例,确认阴性45例,其中继续追踪57例(追踪间隔期为8周),永久屏蔽18例。结论初筛阳性假阳性率较高,多数献血者可进行归队检测。

Objective To improve confirmatory screening tests and the research on reentry strategies,in order to protect the rights of blood donors. Methods A total of 22,287 blood samples were screened for HBV with ELISA and TMA nucleic acid detection purchased from different manufacturers. If either was positive,the sample would be sent to the Institute of Transfusion Medicine for a neutralization test. According to the result,the samples would be tracked and tested. Results Of all 22,287 cases that underwent serological detection,75 positive samples were screened and 30 were affirmative in the following test,the rest of the 45 samples were negative. Of the 75,57 were tracked every 2 months and the remaining 18 samples were permanently deferred. Conclusion Majority of blood donors should be reentered due to the high rates of false positives.