599例住院结核病人回顾性临床分析

Retrospectively clinical analysis of 599 hospitalized patients with tuberculosis

目的：了解川北地区结核病的临床特点,为该地区结核病的防治提供依据。方法：回顾性分析川北医学院附属医院2003年住院结核患者的性别、年龄、临床诊断;复治结核患者的初次治疗情况。结果：599例病人中,男女之比为1.58∶1,15~65岁患者共占84.82%;老年病人中,男性病人明显多于女性。结核病变主要为Ⅲ型肺结核。复治结核病人占总数的11.02%,复治患者见于15~75岁,比例随年龄增加而增高。复治结核病人初次治疗失败的主要原因治疗方案不合理及疗程不足。结论：在川北地区结核主要见于中青年男性,老年患者中男性明显多于女性;结核病变仍以以肺及胸腔为主;复治病例主要见于中老年患者,导致结核初治失败的主要原因是方案不合理及疗程不足。在该地区加强宣传提高民众对结核相关知识的知晓度对于结核的成功治疗和防止耐药结核菌的产生和传播有重要意义。

Objective： To investigate the various clinical characteristics of patients with tuberculosis（ TB） in Chuanbei areaand provide evidences for tuberculosis management. Methods： the age,gender,anddiagnosis information of 599 patients with TB hospitalized in 2013 were retrospectively analysed. And the initial treatment information of recurrent TB patients was also analyzed. Results： Among the 599 patients,the ratio of male to female is 1. 58∶ 1,the patients between 15 to 65 years old accounted for 84. 82%,and over 65 years old of age male patients were significantly more than women. The lesion of tuberculosis mainly involved the lung and the pleural,and the type Ⅲ tuberculosis was the majority. Among all the TB patients,recurrent tuberculosis accounted for 11. 02% and no re-treated cases were found in patients down 15 and over 75 years old. Between the ages of 15 to 75 years,the potion of the recurrent TB patients was increased with age. Among patients with re-treated TB,treatment interruption and irregular medication were major reasons for failure of initial treatment. Conclusion： In Chuanbei areas,the majority TB patients were the young and middle-aged males. And among aged TB patients,male were significantly more than female. The lesion of tuberculosis mainly involved the lung and the pleural. Among patients with re-treated TB,treatment interruption and irregular medication were major reasons for failure of treatment. It is important for successful treatment and prevention of emergence and spread of drug-resistance TB to strengthen publicity and enhance the awareness of knowledge about tuberculosis in the less developed Chuanbei rual areas.