阿司匹林和低分子肝素治疗习惯性流产的临床效果

Clinical effect of aspirin and olw molecular weight heparin on habitual abortion

目的探讨阿司匹林和低分子肝素治疗习惯性流产的临床效果。方法选取2013年1月至2014年6月夏邑县第三人民医院收治的习惯性流产患者50例,随机将其分为观察组与对照组,每组25例。对照组以小剂量阿司匹林进行治疗,观察组在此基础上联合低分子肝素进行治疗,比较两组患者的治疗效果。结果观察组足月产率为76%,活产率为96%,流产率为4%,抗体清除率为72%;对照组足月产率为48%,活产率为72%,流产率为20%,抗体清除率为40%,组间比较差异有统计学意义(P<0.05)。结论阿司匹林和低分子肝素治疗习惯性流产临床效果显著,优于单项阿司匹林治疗。

Objective To investigate the clinical effect of aspirin and low molecular weight heparin on habitual abortion.Methods Fifty patients with habitual abortion in the third people＇s hospital of xiayi from January 2013 to June 2014 were randomly divided into observation group and control group with 25 cases in each group. The control group was treated with small dose aspirin,and the observation group was treated with low molecular weight heparin in addition. The effects of the two groups were compared. Results In the observation group,the term birth rate was 76%,the live birth rate was 96%,the abortion rate was4%,the antibody clearance rate was 72%; in the control group,the term birth rate was 48%,the live birth rate was 72%,the abortion rate was 20%,and the antibody clearance rate was 40%,the differences between the two groups were significant（ P〈0. 05）. Conclusion Aspirin and low molecular weight heparin in the treatment of habitual abortion clinical effect is significantly better than the single aspirin therapy.