RDW和hs-CRP水平在急性心肌梗死中的表达及与冠状动脉狭窄程度的关系

Expressions of RDW and hs-CRP in Acute Myocardial Infarction and Their Relationship with Degree of Coronary Artery Stenosis

目的:研究红细胞分布宽度(RDW)和高敏C反应蛋白(hs-CRP)水平在急性心肌梗死中的表达及与冠状动脉狭窄程度的关系。方法:选取2010年1月到2015年1月我院收治的急性心肌梗死患者300例(研究组),另选取单纯心绞痛患者300例(对照组),比较两组RDW、hs-CRP、Gensini评分和冠状动脉病变支数,并分析RDW、hs-CRP和Gensini评分、冠状动脉病变支数的关系。结果:研究组RDW、hs-CRP、Gensini评分和冠状动脉病变支数均显著高于对照组,两组比较差异具有统计学意义(P<0.05);冠状动脉Gensini评分和病变支数与RDW、hs-CRP呈正相关关系(r=0.58,0.69,0.49,0.57,P<0.05),同时RDW和hs-CRP呈正相关关系(P<0.05)。结论:急性心肌梗死患者会出现RDW和hs-CRP水平增高现象,和冠状动脉狭窄程度呈正相关关系。

Objective： To study the red blood cell distribution width（RDW） and high-sensitivity c-reactive protein（hs-CRP） levels in acute myocardial infarction（AMI） expression and their relationship with the degree of coronary artery stenosis. Methods： A total of300 patients with acute myocardial infarction, who were admitted to Kaifeng Second People＇s Hospital of Henan Province from January2010 to January 2015, were chosen as study group, another 300 patients with pure angina pectoris, as control group. The RDW, hs-CRP,the Gensini score and coronary artery lesion counts of the two groups were compared and the relationship of RDW and hs-CRP with Gensini score and coronary artery lesion counts were analyzed. Results： RDW, hs-CRP, the Gensini score and coronary artery lesion count of the study group were significantly higher than those of the control group, with statistically significant difference（P〈0.05）.Gensini score and coronary artery lesion count have positive correlation with RDW and hs-CRP（r=0.58, 0.69, 0.58, 0.69, P〈0.05）, and the RDW was positively correlated with hs-CRP（P〈0.05）. Conclusion： RDW and hs-CRP in patients with acute myocardial infarction are increased, which has a positively relationship with degree of coronary artery stenosis.