摘要
目的:系统评价糖皮质激素在儿童支原体肺炎治疗中的作用。方法:计算机检索中英文数据库,依据纳入指标及排除指标纳入文献,根据Jadad评分及偏倚分析对文献进行评价,运用Revman5.0进行系统评价。结果:糖皮质激素对儿童支原体肺炎患者的体温及CRP调节具有特异质,进行随机效应模型评价,结果分别为-1.4及-0.42,P<0.05,具有统计学意义。亚组分析氢化可的松、甲泼尼松龙及地塞米松对体温的调节结果均有显著性差异,氢化可的松效果最好;结论:糖皮质激素在儿童支原体肺炎治疗中对体温和CRP的调节有积极的意义。
Objective: To evaluate the effect of glucocorticosteroid on children mycoplasmal pneumonia. Methods: Meta-analysis was performed by evaluating 19 controlled trials of the effect of glucocorticosteroid on children mycoplasmal pneumonia. Results: The results of pooled effects of glucocorticosteroid on body temperature and CRP control were-1.4 and-0.42 respectively, which showed significant difference. Conclusion: Glucocorticosteroid has a significant effect on children mycoplasmal pneumonia in body temperature and CRP control.
出处
《临床药物治疗杂志》
2016年第1期28-34,共7页
Clinical Medication Journal
基金
辽宁省"基于GAP国际认证的新药临床评价共性技术及应用"课题项目(2014226033)
关键词
糖皮质激素
支原体肺炎
系统评价
glucocorticosteroid
mycoplasmal pneumonia
meta-analysis