糖尿病早期肾损伤应用尿糖、尿微量白蛋白联合检验诊断的效果分析

Efficacy on the Combiled Detection of Urine Suger and Microalbuminuria for Diagnosis of Diabetic Renal Damage

目的应用尿糖、尿微量白蛋白联合检验诊断糖尿病早期肾损伤患者,对其的临床效果进行观察。方法选取2014年1月—2015年1月于该院收治的50例糖尿病患者作为研究对象设为实验组,其中男性患者30例,女性患者20例。另外选取同期健康人群50例设为参照组,男性22例,女性28例。分别对两组观察对象的尿糖和尿微量白蛋白进行检测,并比较检测结果进行分析。结果实验组50例糖尿病组患者检测尿糖含量(3.15±1.94)mol/L,健康组则为(1.28±0.44)mol/L,糖尿病组尿糖明显比健康组尿糖上升。在糖尿病组患者中,糖尿病组患者尿微量白蛋白含量(39.3±7.8)mol/L,而非糖尿病组患者尿微量白蛋白含量(17.5±3.4)mol/L。两组尿糖和尿微量白蛋白水平的比较,实验组患者尿糖和尿微量白蛋白的水平明显高于参照组,而且其组间数据的差异具有统计学意义(P<0.05)。实验组尿糖和尿微量白蛋白阳性为84.00%(42/50),72.00%(38/50)。参照组尿糖和尿微量白蛋白检验结果显示阳性率均为0。结论尿糖、尿白蛋白联合检验值得在临床上推广用于糖尿病早期肾损伤患者的诊断。

Objective To apply urine early diabetic kidney damage, urinary albumin joint laboratory diagnosis, clinical effect observed. Methods January 2013- January 2014 50 diabetic patients were divided into experimental group, while 50 cases of healthy people choose the same period as the reference group. The two groups were observed object of urine and urinary microalbumin testing, and compare the test results. Results The experimental group detecting urine sugar levels（3.15 ± 1.94） mol / L, healthy group（1.28 ± 0.44） mol / L, the diabetic group significantly increased urine urine than healthy group. In diabetic patients, the experimental group urinary albumin content（39.3 ±7.8） mol / L, and the content of urinary albumin in patients in the control group（17.5±3.4） mol / L. Were compared urine and urinary albumin levels, urine and urinary albumin levels in patients in the experimental group was significantly higher than the reference group, and the difference was statistically significant formation data（P〈0.05）. Experimental urine and urine albumin-positive was 84.00%（42/50）, 72.00%（38/50）. Reference group urine and urinary albumin-positive rate is 0. Conclusion The combined detection of urine and urinary albumin for early diagnosis of renal damagehas important clinical value for the diagnosis of early diabetic renal damage.