F波在糖尿病亚临床神经病变诊断评估中的应用

F Wave in Subclinical Diabetic Neuropathy Diagnostic Evaluation

目的研究F波在糖尿病亚临床周围神经病变诊断评估中的应用。方法选取该院2015年4—10月收治的2型糖尿病患者40例作为研究对象。按有无周围神经损害症状分为无症状组与有症状组,各20例,另选40例健康志愿者作为对照组,检测上肢正中神经和下肢胫后神经F波,检测参数主要包括:F波传导速度(Fev)、平均潜伏期(Flmean)、F波出现率(Fpresent)、F波最短潜伏期(Flmin)。结果在正中神经Flmin、Flmean、Fchd方面,对照组Flmin(20.17±1.80)ms、Flmean(22.28±1.15)、Fchd(2.75±1.03)显著低于无症状组Flmin(21.44±2.23)ms、Flmean(23.33±2.23)、Fchd(5.38±3.50),在Fpresent上,对照组显著高于无症状组,差异有统计学意义(P<0.05)。在胫后神经Flmin、Flmean、Fchd方面,对照组Flmean(45.28±1.15)、Flmin(43.17±1.80)、Fchd(3.75±1.03)显著低于无症状组Flmean(49.33±2.23)、Flmin(45.44±2.33)、Fchd(7.38±3.50),在Fpresent上,对照组显著高于无症状组,差异有统计学意义(P<0.05)。在正中神经和胫后神经Flmin、Flmean、Fchd方面,有症状组显著高于无症状组,差异有统计学意义(P<0.05)。结论在早期诊断DPN方面,F波是较为敏感的指标,有利于发现亚临床病变。

Objective To study the F wave in diagnostic evaluation of peripheral neuropathy subclinical diabetic. Methods Our hospital in April 2015 ~ October 2015 admitted 40 patients with type 2 diabetes study. According to whether asymptomatic peripheral nerve damage symptoms are divided into groups with symptomatic group, the 20 cases, 40 cases of alternative healthy volunteers as a control group, after the detection of the upper limbs and lower limbs median nerve tibial nerve F wave detection parameters include： F wave velocity（Fev）, the average incubation period（Flmean）, F wave occurrence rate（Fpresent）, F wave minimum latency（Flmin）. Results The median nerve Flmin, Flmean, Fchd aspect, the control group Flmin（20.17±1.80） ms, Flmean（22.28±1.15）, Fchd（2.75±1.03） was significantly lower than the asymptomatic group Flmin（21.44 ± 2.23） ms, Flmean（23.33±2.23）, Fchd（5.38±3.50）, in the Fpresent, the control group was significantly higher than the asymptomatic group with statistical significance（P〈0.05）. In the posterior tibial nerve Flmin, Flmean, Fchd aspect,the control group Flmean（45.28±1.15）, Flmin（43.17±1.80）, Fchd（3.75±1.03） was significantly lower than the asymptomatic group Flmean（49.33±2.23）, Flmin（45.44±2.33）, Fchd（7.38±3.50）, in the Fpresent, the control group was significantly higher than the asymptomatic group with statistical significance（P〈0.05）. After the median nerve and tibial nerve Flmin,Flmean, Fchd aspect, with symptoms was significantly higher than the asymptomatic group with statistical significance（P〈0.05）. Conclusion In terms of early diagnosis of DPN, F wave is a more sensitive indicator of subclinical lesions in favor.