保妇康栓联合雌激素软膏治疗老年糖尿病患者阴道炎的安全性

Bao fu Kang Shuan the Safety of Combined Estrogen Ointment Treatment in Elderly Patients with Diabetes Vaginitis

目的研究保妇康栓联合雌激素软膏治疗老年糖尿病患者阴道炎的安全性。方法选取2014年10月—2015年9月该院收治的患有阴道炎的老年糖尿病患者260例,根据治疗方法的不同将患者分为两组,每组130例。采用雌激素软膏治疗的患者为单用药组,采用保妇康栓联合雌激素治疗的患者为联合用药组。观察两组患者的治疗效果、治疗后的阴道症状、生活质量及不良反应的情况。结果联合用药组治疗的总有效率显著高于单用药组(P<0.05),治疗后的阴道健康状况的评分明显高于单用药组(P<0.05),阴道炎性症状的评分和不良反应发生率均显著低于单用药组(P<0.05),联合用药组患者的生理功能、生理职能、躯体疼痛、总体健康、活力、社会功能、精神健康等生活质量方面的评分及总分均明显优于单用药组(P<0.05)。结论保妇康栓联合雌激素软膏治疗老年糖尿病患者阴道炎的疗效显著,有效改善了患者的阴道症状,提高了患者的生活质量,且不良反应少,是一种安全、有效的治疗方法。

Objective To study the bao fu Kang.Shuan the safety of combined estrogen ointment treatment in elderly pa- tients with diabetes vaginitis. Methods Selection in October 2014 - September 2015 our hospital 260 cases of elderly dia- betes patients with vaginitis, according to different treatment methods of divided the patients into two groups, 130 cases in each group. In patients treated with estrogen ointment for single drug groups, adopt bao fu Kang Shuan combined estrogen therapy of patients in combination group. To observe the therapeutic effect of two groups of patients, after treatment of vagi- nal symptoms, life quality and adverse reactions. Results The combination treatment group total effective rate is significant- ly higher than the single drug group （P 〈 0.05）, after treatment of vaginal health score significantly higher than the single drug group （P 〈 0.05）, vaginal inflammatory symptoms score and the incidence of adverse reactions were significantly lower than that of single drug group （P 〈 0.05）, combined treatment group patients physiological function, physiological function, body pain, general health, vitality, social function, mental health and life quality score and total score were significantly bet- ter than the single drug group （P 〈 0.05）. Conclusion Bao fu Kang Shuan combined estrogen ointment treatment in elderly patients with diabetes vaginitis curative effect is distinct, effectively improve the patient＇s vaginal symptoms, improve the life quality of patients, and less adverse reaction, is a safe and effective treatment method.