重组人干扰素局封治疗尖锐湿疣疗效观察

Effects of recombinant human interferon in treatment of condyloma acuminatum

目的:探讨应用重组人干扰素治疗尖锐湿疣的疗效。方法:共有119例病人完成观察,治疗组59例,对照组60例。治疗组局部麻醉后用二氧化碳去除疣体,疣体基部用重组人干扰素局封,隔天一次,同时口服贞芪扶正胶囊,共8周。对照组用二氧化碳去除疣体,同时口服贞芪扶正胶囊,连续应用8周。结果:治疗组与对照组总有效率分别为83.05%、38.33%,治疗组明显高于对照组(P<0.05)。结论:重组人干扰素局封联合贞芪扶正胶囊治疗尖锐湿疣疗效优于单用贞芪扶正胶囊,复发率低。

Objectives： To investigate the therapeutic effect of recombinant human interferon for condyloma acuminatum. Methods： 119 patients were observed,including treatment group（ n = 59） and control group（ n =60）. Treatment group received carbon dioxide after local anesthesia to remove wart body and verrucous body was topically obturated with recombinant human interferon,every other day,also orally took Zhenqi Fuzheng capsule for a total of 8 weeks. The control group received carbon dioxide to remove wart and orally took Zhenqi Fuzheng capsule for 8 weeks. Results： The total effective rate of the treatment group and the control group were 83. 05% and38. 33% respectively,and the treatment group was significantly higher than the control group（ P〈0. 05）.Conclusion： Recombinant human interferon combined with Zhenqi Fuzheng capsule is of better curative effect than using Shenqi Fuzheng capsule alone,with low recurrence rate