1426例成人呼吸系统感染住院患者肺炎衣原体感染状况分析

Prevalence status of Chlamydia pneumoniae infection in 1426 adults with respiratory infections

目的了解成人急慢性呼吸系统感染患者肺炎衣原体(Chlamydia pneumoniae,CP)Ig M抗体阳性率在性别、年龄和季节分布上的趋势。方法采用ELISA法检测1426例住院治疗的呼吸系统感染患者血清CP Ig M抗体。结果 1426例CP Ig M抗体阳性率为13.7%;男女患者CP Ig M抗体阳性率差异无统计学意义;各年龄组中,青年组CP Ig M抗体阳性率为37.4%,明显高于中年组和老年组;春、夏季CP Ig M抗体阳性率分别为16.7%和22.5%,明显高于秋、冬季。结论对于在春、夏季出现的急慢性呼吸系统感染的青年患者应考虑CP感染的可能性。

Objective To investigate the distribution of the prevalence of Chlamydia pneumoniae（CP）Ig M antibodies by gender, age and season in hospitalized adults with acute or chronic respiratory infections. Methods ELISA was used to detect CP Ig M antibodies in 1426 hospitalized patients with respiratory infections. Results The seroprevalence of CP Ig M antibodies in 1426 patients was 13.7%. No significant difference was found between males and females. The seroprevalence of CP Ig M antibodies in young patients was 37.4%, significantly higher than those in the middle-aged patients and the elderly patients. The seroprevalences of CP Ig M antibodies in patients with respiratory infections occurring in spring and summer were 16.7% and 22.5%, respectively, significantly higher than those in patients with respiratory infections occurring in autumn and winter. Conclusion CP infection should be taken into consideration for young patients with acute or chronic respiratory infections occurring in spring and summer.