伤科黄水湿敷联合青霉素钠注射液治疗下肢急性蜂窝织炎临床观察

Clinical observation of acute lower limb cellulitis treated with wet dressing of the herbal yellow-water combined with benzylpenicillin sodium injection

目的探讨伤科黄水湿敷联合青霉素钠注射液治疗下肢急性蜂窝织炎的临床疗效。方法将80例下肢急性蜂窝织炎患者随机分为治疗组和对照组各40例。两组均以注射用青霉素钠640万U+生理盐水100 mL,静脉滴注,Q8h;同时治疗组和对照组分别予以伤科黄水和50%硫酸镁局部湿敷治疗,bid。观察两组白细胞计数、症状减轻时间、治愈时间、局部疼痛积分及治疗效果。结果治疗组临床有效率为95.00%(38/40),对照组有效率90.00%(36/40),差异具有统计学意义(P<0.05)。两组治疗后WBC计数均较治疗前降低(P<0.05);治疗组治疗后综合症状减轻时间、治愈时间较对照组缩短(P<0.05)。两组治疗后第3、7天局部疼痛积分与治疗前比较均明显降低(P<0.05);两组患者治疗后WBC计数比较无统计学差异。结论伤科黄水联合青霉素钠注射液治疗下肢急性蜂窝织炎疗效肯定,可促进炎症消退,有效缓解患肢局部疼痛。

Objective To investigate the effect of the herbal yellow-water（traditional Chinese medicine） combined with benzylpenicillin sodium injection on acute lower limb cellulitis. Methods Totally 80 cases of acute lower limb cellulitis patients were randomized into a treatment group and a control group,with 40 cases in each group.Both groups were treated with 6.4 million U of benzylpenicillin sodium for intravenous drip,Q8 h. At the same time, the patients in treatment group were given herbal yellow-water wet dressing, and the patients in control group were treated with 50% magnesium sulfate for wet dressing. Leucocyte count, the symptom relief time, the healing time, the local pain score and the clinical efficacy in two groups were collected and analyzed. Results The clinical efficiency in treatment group and control group were 95%（38 / 40） and 90%（36 / 40）, the difference was statistically significant（P 〈0.05）. Symptom relief time, healing time in treatment group were shorter than that in control group（P〈 0.05）. Local pain scores on the 3rd, 7th day in treatment group were significantly lower than those in control group..No significant difference was found between the two groups in leucocyte count. Conclusion In our study,the traditional Chinese medicine,herbal yellow-water combined with Benzylpenicillin Sodium Injection showed good clinical efficacy in the treatment of acute lower limb cellulitis.