经尿道前列腺电切术与1470nm半导体激光汽化术治疗前列腺增生的疗效比较

Comparison of the efficacy between transurethral resection of prostate and 1470 nm diode laser in the treatment of benign prostatic hyperplasia

目的对经尿道前列腺电切术和1470 nm半导体激光汽化术治疗前列腺增生的临床疗效的比较。方法收集2014~2015年采用不同方法治疗前列腺增生患者的临床资料,选择1470 nm半导体激光汽化术治疗和TURP治疗的BPH患者各50例,分治疗组和对照组,2组术前临床参数比较无统计学意义（P〉0.05）。对两组手术情况、随访情况及并发症发生率进行比较。结果采用1470 nm半导体激光汽化术治疗组显示良好临床效果,两组在手术时间、术中出血量、术后留置导尿管时间和术后住院时间的差异均有统计学学意义（P〈0.05）。术后3个月随访,2组IPSS、Qmax、RUV与术前相比及组间术后相比差异均有显著性意义（P〈0.05）;治疗组与对照组并发症发生率分别为6%和26%,差异有统计学意义（P〈0.05）。结论 TUPR和1470 nm半导体激光汽化术均能有效的治疗前列腺增生,但1470 nm半导体激光汽化术术中出血量少,导尿管留置时间短,并发症少,安全性高,效果更好。

Objective To compare the clinical efficacy of transurethral resection of prostate and 1470 nm diode laser for treatment of benign prostatic hyperplasia. Methods 100 cases of benign prostatic hyperplasia were assigned to 1470 nm semiconductor laser vaporization group（treatment group, n =50） and transurethral resection of the prostate（TURP） group（control group, n =50）. The preoperative clinical parameters of the two groups were comparable not statistically significant. Then operation condition, follow-up and complication rate were compared between two groups. The clinical effect of two group was recorded and analyzed. Results The operation time, intraoperative blood loss,postoperative indwelling catheter time and postoperative hospital were statistically significant between two groups（P〈0.05）. After 3 months follow-up, there were statistically significant differences in IPSS,Qmax, RUVs between two groups（P〈0.05）. The complications in the treatment group and the control group were 6% and 26%, respectively（P 〈0.05）. Conclusion Both surgical approaches of 1470 nm diode laser and TURP showed good effect for treating BPH, but the 1470 nm diode laser vaporization demonstrated better efficacy with less blood loss, shorter catheter indwelling time, lower complication rate.