活血清热祛湿法治疗淤胆型肝炎随机对照研究

Randomized Control Trials of Therapy with the Method of Reactivating the Blood,Dispelling the Toxic Heat and Dissolving the Dampness on Cholestatic Hepatitis

目的:观察活血清热祛湿法治疗淤胆型肝炎的临床疗效。方法:将符合纳入标准的60例患者随机分为对照组和治疗组,每组各30例。对照组以西药常规对症治疗,治疗组在对照组基础上加用中药颗粒剂,治疗周期为4周。结果:在疗效方面,对照组总有效率为83.3%,治疗组总有效率为96.7%,两组差异不显著(P>0.05)。在中医证候疗效方面,对照组总有效率为76.7%,治疗组总有效率为96.7%,两组差异显著(P<0.05)。在中医证候积分方面,两组差异显著(P<0.05)。在改善部分中医症状方面,两组差异显著(P<0.05)。结论:中西医结合治疗淤胆型肝炎对中医证候积分的改善、有效率等方面优于单纯西药组。中医辨证施治,活血清热祛湿法在治疗淤胆型肝炎方面值得积极推广。

Objective：To observe the effect of the method of reactivating the blood,dispelling the toxic heat and dissolving the dampness on treatment of cholestatic hepatitis. Methods：The 60 patients who met the inclusion criteria were randomly divided into the control group and the treatment group（each n=30）.The control group was given symptomatic treatment of Western medicine and glucocorticoid. The treatment group was given herb decoction besides symptomatic treatment of Western medicine as the control group for 4weeks. Results：On the effect of Western medicine,the efficacy rate of the control group was 83.3% and the efficacy rate of the treatment group was 96.7%,both without statiscal significance（P〉0.05）.The scores of traditional Chinese medicine sign of both of the groups had statiscal significance（P〈0.05）.On the effect of improving parts of traditional Chinese medicine signs,both of the groups had statiscal significance（P〈0.05）.Conclusions：The treatment on patients with cholestatic hepatitis using the combination of Western medicine and traditional medicine is more effective than Western medicine alone,with declining of the score of traditional Chinese medicine signs and increasing the effectiveness rate. The dialectic method of traditional Chinese medicine in reactivating the blood,dispelling the toxic heat and dissolving the dampness is worth promoting in the clinical treatment of cholestatic hepatitis.