新疆南疆地区犬戊型肝炎病毒的血清学调查

Seroepidemiological Survey on Hepatitis E Virus Infection of Dogs in Nanjiang Region of Xinjiang

为了解新疆南疆地区犬戊型肝炎病毒（HEV）感染的情况及流行特点,为其科学防控提供参考依据,采用酶联免疫吸附试验法,对新疆南疆地区采集的160份犬血清进行HEV IgG抗体检测,并比较不同来源、品种、年龄及性别犬HEV IgG抗体的阳性率差异。结果表明：160份被检血清中有21份HEV IgG抗体呈阳性,阳性率为13.13%。其中,农村饲养犬的阳性率为25.46%（14/55）,城市家养犬为6.67%（7/105）,差异极显著（P〈0.01）;5岁以上、2-5岁和2岁以下犬的抗体阳性率分别为10.71%、16.84%和5.41%,差异显著（P〈0.05）;贵宾犬、金毛猎犬、京巴犬、牧羊犬和其他品种犬的抗体阳性率分别为25.71%、6.52%、7.90%、0%和18.18%,金毛猎犬和金巴犬间差异不显著（P〉0.05）,其他各品种间差异极显著（P〈0.01）;雄性犬和雌性犬的抗体阳性率分别为19.77%和5.41%,差异极显著（P〈0.01）。新疆南疆地区犬已受到HEV感染,应加强人犬之间的公共卫生防护。

To evaluate the infection rate of Hepatitis E virus among dogs in Nanjiang Region of Xinjiang and give an scientific reference for HEV prevention,a total of 160 dog serum samples collected in Nanjiang Region of Xinjiang were tested by ELISA for the presence of IgG antibodies against hepatitis E virus（HEV）,and the positive rate differences were compared based on sample sources,breeds,ages and genders by Chi-square test.The results showed that the total positive rate was 13.13%.21 out of 160 subjects were anti-HEV IgG positive,of which 25.46%（14/55）was in rural feeding dog and 6.67%（7/105）was in urban feeding dog,the difference was highly significant（P〈0.01）;According to the ages,the positive rates of over five years,2to 5years and under 2years old dogs were 10.71%,16.84%and 5.41%,respectively,there were significant difference among each age groups（P〈0.05）;According to the breeds,the positive rates of poodle,golden retriever,jinba dog,sheepdog and others were 25.71%,6.52%,7.90%,0% and 18.18%,respectively,the difference was markedly significant（P〈0.01）except golden retriever and jingba dog;According to the genders,there was also a visible difference（P〈0.01）between male dogs（19.77%）and female dogs（5.41%）.The data confirmed that dog HEV was widespread in Nanjiang Region of Xinjiang,public health protection should be strengthened between human and dog.