374例高龄男性维生素D补充情况的调查

Investigation to Supplement Vitamin D in 374 Men Aged 80 and Over

目的:调查高龄男性血清25-羟基维生素D[25(OH)D]的正常情况,分析补充维生素D与血清25(OH)D的关系。方法:对374例高龄男性维生素D补充情况进行调查,并检测其血清25(OH)D,分析两者间的关系。结果:374例高龄男性中,血清25(OH)D水平正常率仅为10%,其中88例(24%)补充维生素D,其血清25(OH)D水平为(20.82±9.27)ng·ml^(-1),286例(76%)未补充维生素D,其25(OH)D水平为(18.27±8.49)ng·ml^(-1),差异有统计学意义(P<0.05)。结论:高龄男性血清维生素D正常率较低,而补充维生素D可能是提高高龄男性25(OH)D水平的重要方法。

Objective： To evaluate the status of vitamin D normality in men aged 80 and over,and to investigate the association between serum 25-hydroxyvitamin D [25（ OH） D]and supplementing vitamin D. Methods： A cross-sectional survey was conducted in a cohort comprising 374 men aged 80 and over. All participants underwent an questionnaire survey for supplementing vitamin D. Serum 25（ OH） D measurement was conducted,and the association between serum 25（ OH） D and supplementing vitamin D was analyzed. Results： Vitamin D normality[25（ OH） D≥30 ng·ml^-1]were found in 10% men aged 80 and over. In the 88 cases（ 24%） of elderly men who frequently supplement vitamin D with or without supplemental calcium,the mean serum 25（ OH） D level was significantly higher than in the other elderly men [（ 20. 82 ±9. 27） ng·ml^-1vs（ 18. 27 ± 8. 49） ng·ml^-1,P 0. 05]. Conclusion： Vitamin D normality was too low in men aged 80 and over. To supplementing vitamin D might be an effective way to increase the level of serum 25-hydroxyvitamin D.