摘要
目的研究西归对小鼠学习记忆功能的影响。方法采用跳台法、避暗法观察西归对东莨菪碱、亚硝酸钠、乙醇所致小鼠学习记忆功能障碍的影响。结果与模型组及溶剂组比较,西归能明显延长东莨菪碱、亚硝酸钠、乙醇所致学习记忆障碍小鼠的潜伏期(P<0.05或P<0.01),并能降低错误次数(P<0.05或P<0.01)。结论西归具有改善小鼠学习记忆障碍作用。
Objective To study the function of learning and memory of Xigui in mice. Methods The methods of step-down test and step-through test were used to research the effects of Xigui on impairment of learning and memory in mice induced by scopomamine, sodium nitrite and ethanol. Results Compared with the model and solvent group, Xigui could significantly prolong the time of latency and decrease the number of errors on impairment of learning and memory in mice （P〈0.05 or P〈0.01）. Conclusion Xigui could improve the learning and memory disorder of mice.
出处
《中国药物警戒》
2016年第1期5-8,共4页
Chinese Journal of Pharmacovigilance
关键词
西归
小鼠
学习记忆
Xigui
mice
learning and memory
