氨氯地平联合卡托普利治疗高血压合并冠心病疗效观察

Efficacy of amlodipine combined with captopril on hypertension and coronary heart disease

目的探讨氨氯地平联合卡托普利对高血压合并冠心病治疗的临床效果。方法随机选取2012年9月至2014年4月高血压合并冠心病患者90例，按照治疗方案的不同将其分为实验组和对照组，其中实验组患者采用氨氯地平联合卡托普利治疗，对照组患者采用尼群地平、硝酸异山梨酯等药物进行常规治疗，对比两组患者的血压改善情况、心绞痛治疗效果。结果实验组患者的高血压、冠心痛及心电图的治疗效果均明显优于对照组患者，差异有统计学意义（P〈0．05）。结论采用氨氯地平联合卡托普利治疗高血压合并冠心病患者，疗效显著，安全可靠，建议在临床上进一步推广使用。

Objective To investigate the clinical effect of amlodipine combined with captopril on hypertension and coronary heart disease. Methods From September 2012 to April 2014, 90 patients with hypertension and coronary heart disease were selected. According to the different treatment options, they were divided into experiment group and control group. The patients in experiment group were treated with amlodipine combined with captopril, and the patients in the control group were treated with nitrendipine, isosorbide dinitrate and other drugs for routine treatment. The improvement of blood pressure and angina treatment effects were compared. Results The hypertension, coronary heart disease and treatment ECG in experiment group were significantly better than those in the control group, the difference was significant （P 〈 0. 05 ）. Conclusions Amlodipine combined with captopril in treatment of hypertension patients with coronary artery disease, has significant effect, is safe and reliable, so it is recommended to be further promoted in clinical practice.