摘要
组织细胞肉瘤(histiocytic sarcoma,HS)是一种发病率较低的组织细胞性淋巴瘤,其发病隐匿,无特异临床表现及影像学表现,且进展迅速,多数患者确诊时已广泛扩散。目前对HS的诊断多依据其核仁显著,核分裂象多见的形态学表现及至少表达CD68、CD163、溶菌酶中一种的免疫组织化学表现。手术切除、放、化疗是HS较为常见的治疗方式,但目前尚无疗效确切、统一的治疗方案,且预后较差。本研究主要是针对HS的病理研究、诊断、治疗和预后进行综述。
Histiocytic sarcoma is a rare kind of histiocytic lymphoma with an undetectable onset, no specific clinical and imaging mani- festations, and rapid progression. At diagnosis, the histiocytic sarcoma has already spread significantly in most patients. The diagnosis of histiocytic sarcoma depends on the basis of its mitotic figures and at least expression of one of the following: CD68, CD163, and lyso- zyme. Operation excision, radiotherapy, and chemotherapy are currently the more common treatment methods for histiocytic sarco- ma. However, no unified curative and treatment standard exists, and prognosis is poor. This review summarizes the diagnosis and treat- ment of histiocytic sarcoma.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2016年第5期220-222,共3页
Chinese Journal of Clinical Oncology
关键词
组织细胞肉瘤
诊断
病理学表现
histiocytic sarcoma, diagnosis, pathologic features