血清降钙素原与C-反应蛋白对肝癌介入手术患者感染的监测

Infection monitoring by serum procalcitonin and C-reactive protein in patients with liver cancer during interventional procedures

目的分析血清降钙素原(PCT)和C-反应蛋白(CRP)对肝癌介入手术患者感染的监测价值,提高感染的早期诊断水平。方法选择2013年6月-2015年6月行肝癌介入手术住院患者75例,将发生感染的25例肝癌介入手术患者为感染组,未发生感染的50例介入手术患者为未感染组,观察并比较两组患者的血清PCT、CRP水平;采用SPSS 19.0软件进行统计分析。结果感染组患者PCT、CRP水平明显高于未感染组患者,两组比较差异有统计学意义(P<0.05);感染组患者血清PCT、CRP的阳性率分别为88.00%和80.00%,明显高于未感染组患者的16.00%和40.00%,两组比较差异有统计学意义(P<0.05);PCT与CRP的阳性及阴性预测值比较,差异均有统计学意义(P<0.05)。结论血清PCT和CRP测定均有助于肝癌介入手术患者感染的早期诊断,联合测定效果更佳。

OBJECTIVE To analyze the value of serum procalcitonin（PCT）and C-reactive protein in the monitoring of infection in liver cancer patients undergoing interventional procedures and to improve the early diagnosis level of infection.METHODS Totally 75 cases of patients with liver cancer undergoing interventional surgery were selected who were hospitalized in our hospital from Jun.2013 to Jun.2015.The 25 infected cases of patients with liver cancer were set as the infected group and the 50 uninfected patients were set as the non-infected group.Serum PCT and CRP levels were observed and compared between the two groups.The software SPSS 19.0was used for statistical analysis.RESULTS The contents of PCT and CRP in the infected group were significantly higher than that in the non-infected group,the difference between the two groups had statistical significance（P〈0.05）.The positive rates of serum CRP and PCT were 88.00% and 80.00% respectively in the infected groups,significantly higher than those in the non-infected group,and the difference between the two groups had significance（P〈0.05）.The positive predictive rate of PCT and CRP and the negative predictive rate had significance（P〈0.05）.CONCLUSION serum PCT and CRP were all helpful for the early diagnosis of infections in patients with liver cancer and their combination assay was more effective for diagnosis.