癌症患者肺部感染清开灵雾化吸入治疗效果研究

Effect of qingkailing inhalation on prevention and control of pulmonary infections in hospitalized patients with cancer

目的研究癌症住院患者发生肺部感染状况,以及清开灵雾化吸入对癌症患者肺部感染的治疗效果。方法选择2012年11月-2015年11月900例癌症患者,随机分为对照组和观察组,每组各450例,调查两组患者肺部感染率;对两组发生肺部感染患者均给予常规抗菌药物治疗,观察组患者在常规抗菌药物治疗的基础上加清开灵雾化吸入;记录两组患者治疗前及治疗后2、7、15、30d咳嗽、咳痰临床指标,所有数据采用SPSS 17.0软件进行统计分析。结果患者发生肺部感染率观察组为5.56%,对照组为10.22%,比较差异有统计学意义(P<0.05);治疗后两组患者咳嗽、咳痰均有所减轻,观察组患者改善更为明显,两组患者比较,差异有统计学意义(P<0.05);肺部感染患者治疗30d后有效率观察组为96.00%、对照组为86.96%,差异有统计学意义(P<0.05)。结论住院癌症患者给予清开灵雾化吸入给药,可以有效地降低癌症患者肺部感染的发生率,对发生肺部感染患者的控制作用良好。

OBJECTIVE OBJECTIVE To study the situation of pulmonary infections in hospitalized cancer patients and the effect of Qingkailing inhalation for treatment of pulmonary infections in cancer patients.METHODS Totally 900 cases of patients who were diagnosed with cancer in our hospital from Nov.2012 to Nov.2015 were selected.They were randomly divided into the control group and the experimental group,450 cases in each group.The pulmonary infection rate was investigated.The control group used conventional antibiotic treatment.The observation group used Qingkailing atomization and inhalation based on the conventional antibiotic therapy.Clinical indexes of cough and expectoration in the two groups were recorded before treatment and at 2days,7days,15 days,30days after treatment.All data were statistically analyzed by software SPSS 17.0.RESULTS The pulmonary infection rate was 5.56%in the observation group and 10.22%in the control group,the difference between the two groups was significant（P〈0.05）.Cough and expectoration were mitigated after treatment and the improvement in the observation group was significant（P〈0.05）.The effective rate for treatment of pulmonary infection was96.00%in the observation group and 86.96%in the control group after 30 days of treatment,with significance（P〈0.05）.CONCLUSION Qingkailing atomization inhalation for hospitalized cancer patients can effectively reduce the incidence of pulmonary infections in patients with cancer and has good control effect on pulmonary infections.