饮用水中抗生素残留检测方法的研究进展

Progress in Detection Methods of Antibiotic Residues in Drinking Water

抗生素作为一种杀灭或抑制细菌生长的药物,在食品、临床、兽药、农业等方面得到了广泛的应用。然而,抗生素的大量应用导致其残留物进入地表水,进而污染自来水厂水源,而标准的水处理不能将其完全清除,从而对人体产生较大的危害,引起过敏、发热、耐药性甚至再生障碍性贫血等症状。因此,针对饮用水中抗生素残留检测的研究引起了人们广泛的关注。本文对近年来可应用于饮用水中抗生素残留的分析方法(高效液相色谱、太赫兹时域光谱技术、免疫分析法、表面增强拉曼光谱法)的研究进展进行了综述,并对今后抗生素残留检测的发展方向作了展望。

Antibiotics as a type of medicine which kills bacterium or inhibits bacterial growth are widely applied to food, clinical practice, veterinary medicine and agriculture. However, its residue may penetrate surface water and thus portable water source which can not be cleared by standard water treatment method and harmful to human health and will cause disease （e. g. allergy, fever, drug resistance and aplastie anemia）. Therefore, study on detection of antibiotic residues in drinking water attracts increasing attention recently. Here the progress in analysis methods （high-performance liquid chromatography, terahertz time-domain spectroscopy, immunoassays and surface-enhanced Raman spectroscopy） of antibiotic residues in drinking water are reviewed, and development in future as well as the problems of the present situation are also commented.