摘要
逆流色谱(Counter-current chromatography,CCC)是以分析物在液-液两相溶剂中的分配差异为核心的快速分离技术。近年来,逆流色谱对复杂样品的分离,尤其是对天然产物的分离已获得广泛的关注。本文综述了近年来逆流色谱在仪器改进、溶剂体系筛选等领域的研究进展,并介绍了CCC在分离手性化合物中的应用前景。最后,对该领域未来的研究内容进行了展望。
Counter-current chromatography( CCC) is a quick preparative separation technique based on the different partition coefficient in liquid-liquid solvent systems. This paper reviews recent research progress in the region of solvent systems,instruments improvement of CCC. Moreover,some application prospects about enantioseparation of racemic compounds by CCC are also discussed. Finally,the contents and goal of further research in this field is discussed.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2016年第2期319-326,共8页
Chinese Journal of Analytical Chemistry
基金
国家自然科学基金资助项目(No.21532005)~~
关键词
逆流色谱
仪器改进
溶剂体系
手性分离
评述
Counter-current chromatography
Instruments improvement
Solvent systems
Chiral separation
Review
