短效避孕药在未婚女性人工流产术后应用的临床研究

Application of Use of Short-acting Oral Contraceptive Post Abortion in Unmarried Women

目的评估未婚女性人工流产手术后立即口服短效避孕药的临床效果,探讨口服避孕药在未婚女性人流术后的应用。方法纳入2013年6月至2014年6月我科收治未婚的人流术后患者235例,随机分为2组:治疗组(n=124)人流术后当天开始口服妈富隆(1片/d,连用21d)3个周期,同时术后常规口服抗生素及益母草颗粒剂1周;对照组(n=111)术后仅常规口服抗生素及益母草颗粒剂1周。观察并比较2组患者术后阴道流血量、出血时间、月经恢复时间、术后第2周子宫内膜厚度、尿h CG转阴情况和盆腔感染情况等资料。结果与对照组相比,观察组的术后阴道流血量少,出血时间短,月经恢复时间短,术后第2周子宫内膜更厚、术后第2周尿h CG转阴率高,盆腔感染及其他并发症更少,差异均有统计学意义(P<0.05)。结论未婚女性人工流产手术后立即给予口服短效避孕药是安全的,术后阴道流血少,月经恢复时间准确,促进子宫内膜修复,并有一定的预防盆腔感染作用,符合生殖健康理念,值得推广。

Objective To estimate the application and advantages of short-acting combined oral contraceptive（ COC）post abortion in unmarried women. Methods A total of 235 cases of unmarried women who terminated the pregnant by artificial abortion,were randomly divided into Group A（ taking Marvelon after surgery,n = 124） and Group B（ control group,n = 111）.Hormone drugs were administrated to patients in Group A immediately after induced abortion for three cycles.Bleeding time,time of menstruation turn over,menstrual disorder,the pregnancy,endometrial thickness and adverse drug reactions were observed.Results The time of bleeding and menstruation turn over in group A was less than group B（ P〈0. 05）,the incidences of menstrual disorder in group A was lower than group B（ P〈0. 05）. The time of bleeding,menstruation turn over and the incidences of menstrual disorder in group A was better than those in group B. Conclusion Application of short-acting COC immediately after artificial abortion was reasonable,beneficial and safe in protecting unmarried women＇s reproductive health.