腰大池引流联合鞘内万古霉素注射在颅内感染中的应用

Application of integration of lumbar cisterna drainage and intrathecal Vancomycin injection in intracrainial infection

目的探讨腰大池引流联合鞘内万古霉素注射在颅内感染中的应用效果。方法对开颅术后颅内感染38例患者给予腰大池引流联合鞘内万古霉素注射治疗。结果 38例患者经改良Rankin量表评分：其中恢复良好24例（63.1%）,m Rs为0-1,轻度残疾6例（15.8%）,m Rs为2,中度残疾5例（13.1%）,m RA为3,重度残疾1例（2.6%）,m Rs为4,植物状态生存1例（2.6%）,m Rs为5,死亡1例（2.6%）。结论腰大池引流联合鞘内万古霉素注射对于颅内感染患者是有效并切实可行的,可提高治愈率,降低病死率,具有经济、便于操作等优点。

Objectives Discussion of application of integration of lumbar cisterna drainage and intrathecal vancomycin injection in intracrainial infection.Methods Conduct retrospective analysis of clinical materials of 38 patients who got intracrainial infection after crainotomy and were provided with integration of lumbar cisterna drainage and intrathecal vancomycin injection.Results 38 patients were scored by modified Rankin Scale：good recovery 24cases（63.1%）,m Rs was 0-1,slight disability 6 cases（15.8%）,m Rs was 2,moderate disability 5 cases（13.1%）,m Rs was 3,severe disability 1 case（2.6%）,m Rs was 4,vegetative 1 case（2.6%）,m Rs was 5,death 1 case（2.6%）.Conclusion Integration of lumbar cisterna drainage and intrathecal vancomycin injection are effective and practical for intracrainial infection patients,it can improve recovery rate of intracrainial infection and reduce death rate. It is economical and easy to be operated.