卒中后抑郁的发生与卒中位置 次数 病灶个数的关系探讨

Relationship with the stroke position,stroke frequency,the number of lesions of depression after stroke

目的探讨卒中后抑郁的发生与卒中位置、次数、病灶个数的关系。方法选择120例急性脑卒中患者,在患者发病2周时,采用汉密尔顿抑郁量表(HAMD)进行评分,分为卒中后抑郁组(post-stroke depression,PSD)和非PSD组。计算PSD的发生率,并比较2组患者的脑卒中的发病次数、发病部位,了解卒中位置与PSD发生的相关性。结果 PSD总的发生率为38.3%,其中轻度抑郁12例(26.09%),中度抑郁为24例(52.17%),重度抑郁10例(21.74%);卒中次数越多、卒中病灶个数越多,越容易发生PSD(P<0.05);从卒中位置来看,抑郁组和无抑郁组的卒中位置左侧明显高于右侧和双侧;多病灶患者PSD的临床发病率要高于单病灶患者。结论卒中后抑郁的发生与卒中位置有关,与卒中次数、病灶个数呈正相关。

Objective To investigate the Relationship with the stroke position, stroke frequency,the number of lesions of depression after stroke. Methods According to the scores of Hamilton Depression Scale （HAMD） assessed at 14 d after stroke ,the 120 stroke patients were divided into PSD group and non-PSD group. We calculated the incidence of PSD, and compared between the two groups in Stroke frequency, onset location to learn the relation between PSD and stroke position .Results The incidence of PSD is 38.3% ,including mild patients 12 （26.09%）, moderate patients24 （52.17%） and severe patients 10 （21.74%）. The study found that more stroke and stroke lesion number, more prone to PSD （P 〈 0.05 ）; The lesion location in left hemisphere of the brain has a higher morbidity than that in the both or right hemisphere. The incidence of the PSD with several lesion locations is higher than that of the single lesion location. Conclusion The occurrence of PSD is related to the location of stroke, and were positively correlated with stroke frequency, the number of lesions.