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成年型皮肌炎伴广泛钙质沉着症合并间质性肺炎1例报告

Adult dermatomyositis complicated with extensive calcinosis and interstitial pneumonia:a case report
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摘要 皮肌炎是一种累及肌肉和皮肤的自身免疫性结缔组织病。皮肌炎主要特征是受累肌群的肌无力、疼痛,特异性皮肤表现,伴发热、自身抗体阳性等[1]。钙沉着症在皮肌炎患者中,多见于儿童[2],在成人发生率低,而同时出现间质性肺炎则较罕见,也是死亡的主要原因。
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2016年第3期258-260,共3页 Chinese Journal of Practical Internal Medicine
关键词 皮肌炎 钙质沉着症 间质性肺炎 dtermatomyositis calcinosis interstitial pneumonia
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参考文献9

  • 1Iaccarino L, Ghirardello A, Bettio S, et al. The clinical features, diagnosis and classification of dermatomyositis[J]. J Autoimmun, 2014, 48-49; 122-127.
  • 2Reiter N, EI-Shabrawi L, Leinweber B, et al. Calcinosis cutis: part I. Diagnosticpathway[J].JAmAcad Dermatol, 2011, 65: 1-12.
  • 3Bohan A, Peter JB. Polymyositis and dermatomyositis (First of two parts) [J]. N EnglJ Med, 1975, 292: 344-347.
  • 4Wu H, Geng DY, XuJH. An approach to the development of interstitial lung disease in dermatomyositis: a study of 230 cases in China[J]. J Int Med Res, 2013, 41:493-501.
  • 5Douglas WW, Tazelaar HD, Hartman TE, et al. Polymyositis- dermatomyositis-associated interstitial lung disease [J]. Am J Respir Crit Care Med, 2001,164:1182-1185.
  • 6Tansley SL, McHugh NJ, Wedderburn LR. Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms? [J]. Arthritis Res Ther, 2013, 15:211.
  • 7Valenzuela A, Chung L, Casciola-Roseu L, et al. Identification of clinical features and autoantibodies associated with calcinosis in dermatomyositis[J].JAMA Dermatol, 2014, 150:724-729.
  • 8Chander S, Gordon P. Soft tissue and subcutaneous calcification in connective tissue diseases[J]. Curr Opin Rheumatol, 2012, 24: 158- 164.
  • 9Ichiki Y, Akiyama T, Shimozawa N, et al. An extremely severe case of cutaneous calcinosis with juvenile dermatomyositis, and successful treatment with diltiazem [J]. BrJ Dermatol, 2001, 144: 897-897.

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