基于黏液分泌特性差异的“肺”与“大肠”津液相求的内涵探讨

Discussion on Connotation of Jinyexiangqiu Theory of Lung and Large Intestine Based on Property Difference of Mucus Secretion

"肺与大肠相表里"是中医的重要基础理论,肺主行水,大肠主津,肺与大肠在"津液"代谢方面密切相关。"肺"与"大肠"表里机制的实质研究中,黏液在肺病和肠道疾病中所发挥的作用越来越受到重视,尤其是对肺及肠道不同部位(空肠、回肠、结肠)黏液分泌特性的差异研究逐渐深入,而这恰好与中医"肺"与"大肠"表里之"津液相求"不谋而合。通过比较肺与肠道在杯状细胞、黏蛋白、水通道蛋白和黏液屏障方面的差异,从"津液相求"角度,更好地诠释"肺"与"大肠"的关系。

The theory of lung and large intestine being interior- exterior related is an important basic theory of Traditional Chinese Medicine（ TCM）. Lung governs the movement of water and the large intestine the body fluids. Both of them are closely related with the metabolism of Jinye. In the study of lung and large intestine being interior- exterior related,the mucus plays a more important role in the diseases of lung and intestine,especially with the depth study of the property difference of mucus between lung and intestine（ including jejunum,ileum and colon）,which agrees with the TCM theory of Jinyexiangqiu. Through comparing lung and instestine in the property difference of the goblet cell,mucin,aquaporins and mucus barrier,it would be beneficial to explain the relationship between lung and large intestine from Jinyexiangqiu.