畲药葛花治疗非酒精性脂肪性肝病的临床观察

Clinical Observation of Flower of Pueraria Lobata in Treatment of Non Alcoholic Fatty Liver Patients

目的:观察葛花对非酒精性脂肪性肝病患者的疗效。方法:随机抽取门诊非酒精性脂肪性肝病患者59例,随机分为对照组和实验组,实验组给予辛伐他汀片+葛花颗粒治疗(30 g,2次/d),对照组给予辛伐他汀片+维生素C片+维生素E片治疗,8周为1个疗程。结果:(1)治疗组本组与治疗后相比较,GGT、ALT、AST、TG、TC均有明显统计学差异(P<0.01);(2)与对照组治疗后相比,治疗组GGT、ALT、AST、TG、TC、SOD、MDA及B超变化均有统计学差异(P<0.05)。(3)与对照组相比,治疗组的总有效率及B超有效率均有统计学差异(P<0.05)。结论:葛花对非酒精性脂肪性肝病患者有明显的治疗作用。

Objective： In our experiment,we investigated the effect of the flower of Pueraria lobata on non alcoholic fatty liver. Methods： We randomly divided the sample of 59 cases of outpatients with non alcoholic fatty liver into control group and experimental group. The experimental group was treated with the flower of Pueraria lobata（ 30 g,twic a day） ＋ Simvastatin tablets and the control group given Simvastatin tablets ＋ Vitamin C tablets ＋ Vitamin E. Treatment course was 8weeks. Results：（1）In the experimental group,GGT,ALT,AST,TG and TC were different compare with those befor the treatment（ P〈0. 01）.（2）Compared with the control group,every result was also different after treatment for 8 weeks（ P〈0. 05）.（3）Compared with the control group,the total effective rate and B- mode ultrasonography effective rate of treatment group had significant statistical difference（ P〈0. 05）. Conclusion： The flower of Pueraria lobata can treat the patients of non alcoholic fatty liver.